Association between RhD phenotype and incidence of particular diseases

After rating each particular category of health problems, the subjects were asked to identify which specific disorders they suffered from on the lists of 225 disorders. They were also asked to identify which specialized medical doctors they had to visit regularly (not for prevention) at least once in the past two years from a list of 10 types of specialists. The associations were analyzed with the partial Kendall’s Tau correlation test with age being a covariate. One hundred fifty four (154) of 225 diseases/disorders were reported by at least 10 subjects. Within this subset, 31 significant associations with RhD negativity (21 positive and 10 negative) were expressed in all subjects. In male subjects, the number of significant association was 35 (19 positive and 16 negative) while in female subjects the number of significant associations was 30 (18 positive and 12 negative). The expected number of false significant results for 462 statistical tests was not 96 but 23. For example, RhD negative men more often reported certain mental health disorders including panic disorders, antisocial personality disorders and attention deficits, ticks, fasciculation, thyroiditis, immunity disorders, allergies, especially skin allergies, excessive bleedings, anemia, osteoporosis, liver disease, infectious diseases and acute diarrhea diseases, while they less often reported gall bladder attacks, coeliac disease, maldigestion, malabsobtion, warts, some types of cancers and prostate hypertrophy. RhD negative women reported more frequently psoriasis, constipation and diarrheas, ischemic diseases, type 2 diabetes, some types of cancers, lymphatic nodes swelling, vitamin B deficiency, thrombosis, tonsil stones, too high sex desire, precocious puberty, urinary tract infections, scoliosis and they less often reported hearing loss, weight loss, hypoglycemia, glaucoma, fasciculation and warts. RhD negative subjects had to make more frequent visits to medical professionals specializing in otolaryngology (P = 0.021), psychiatry (P = 0.008), gynecology (P < 0.001), and dermatology (P = 0.014) (the theoretical number of false positive results was 0.5). Table 2 shows the associations between RhD negativity and disease incidences while Table 3 shows the associations between RhD negativity and visiting specialized doctors.

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Worse Health Status and Higher Incidence of Health Disorders in Rhesus Negative Subjects

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How can rh negative people live a happier and healthier life?