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Hemolytic disease caused by Anti C antibodies

Hemolytic disease caused by Anti C antibodies

 Rhesusnegative.net0
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The Rh blood group system consists of 49 defined blood group antigens, among which the five antigens D, C, c, E, and e are the most important.
The terms Rh factor, Rh positive, and Rh negative refer to the Rh(D) antigen only. Antibodies to Rh antigens can be involved in hemolytic transfusion reactions and antibodies to the Rh(D) and Rh(c) antigens confer significant risk of hemolytic disease of the fetus and newborn.

Rh blood group system is a complex blood group system. Rh antibodies are produced in Rh negative individuals following exposure to foreign RBCs after transfusion or pregnancy. Anti C is a rare cause of hemolytic disease of newborn and is very scarcely reported in the literature. The aim of the present case report of Hemolytic disease caused by Anti C antibody is to bring out the fact that antibodies other than anti D should be considered in cases that give a suggestive history but no evidence of Anti D.

Being ccddee indicates me testing negative for the C, D and E antigens. Those are only 3 of the many within the Rh blood group system. If you lack all antigens from the Rh blood group system, you are Rh null which is extremely rare. You are considered Rh Negative when the D is absent. There are however individuals with the C absent, but not the D. This is for everyone lacking the C:

More here:

Anti Rh Hemolytic Disease due to Anti C Antibody: Is Testing for Anti D Antibodies Enough?

See also:

The Rhesus (Rh) blood group is one of the most complex blood groups known in humans. It has remained of primary importance in obstetrics, being the main cause of hemolytic disease of the newborn (HDN). Anti-D causes the most severe form of HDN. Other Rh allo antibodies that are capable of causing severe HDN include anti-c, which clinically is the most important Rh antigen after the D antigen. We report a case of hemolytic disease of the newborn due to Rh anti-c in an infant of an Rh positive mother.
Source:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710558/?fbclid=IwAR0bhKlvMyyTZ0lzgD93RrqKURAkD5964HStKBMshXxWFGxqKTx34nTvnA0#CR2


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