The Rh Negative Blog

Is it true that “Rh- blood cannot be cloned”?

First of all:

You don’t clone blood.

You clone nucleic acid segments or genes or possibly the expression of proteins.

But that’s beside the point (I’m sure that whoever came up with the claim knew that).

HOWEVER:

This might be the study which the claim was based on:

The mRNA transcript for Rh13 was present in reticulocytes from RhD-positive individuals, but was absent from the reticulocytes of RhD-negative individuals. Using conventional screening of genomic libraries, as well as PCR cloning, partial genomic clones for these two Rh cDNAs were obtained. Based on PCR analysis and Southern blots, the Rh21 gene was present in all individuals, but an intact Rh13 gene was only present in RhD-positive and not RhD-negative individuals.

For more details, use the search function on this blog (don’t worry: I won’t bore you with it in this post).