For another study indicating longevity in blood type B, see the Japanese study on this blog.
The following indicates blood type B not doing that well in Europe:
In conclusion, our retrospective survey showed that the percentage of people with group B blood declined with age. Group AB also had a negative correlation with age, although this was less pronounced: indeed, its effects were conditioned by gender, being significant only in females. The proportion of subjects with group A blood increased with age, but again this effect was significant only in females. Thus a conditioning effect of gender was evident for both A and AB groups. We have no explanations for these observations, although an association between B blood type and some aging-associated degenerative disorders, such as Parkinson’s disease, has been found.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385082/
Rh negative blood has not been examined in the above study.
ADDED:
This is not the only European study indicating lower life expectancy in Europe for blood type B:
To assess the observation that blood type B might be a marker for longevity, we reviewed the records and determined the ABO blood types of all patients who died in our hospital in 2004. Age was stratified by decade of death, and linear regressions were calculated by ABO percentage. ABO survival curves were compared. In 2004, 906 patients died; 35 were excluded (stillborn infants). Of the remaining 871 patients, ABO types were available for 772 (88.6%). The percentage of patients with group B blood declined with age (P < .01). None of the other blood type percentages had a statistically significant increase or decrease. The group B survival curve was statistically worse than non-B groups (P ≤ .01); there were no differences in survival among groups A, O, and AB (P =.47). In our patient population, the percentage of patients with group B blood declines with age. The survival curve in group B was worse than that in groups A, O, and AB. These findings suggest that in our patient population, blood group B is not a marker for longevity but may be a marker for earlier death.
https://pubmed.ncbi.nlm.nih.gov/21173130/
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well, both studies are based on the patients/people seen at two different hospitals. the first listed is a 2014 study of data from the Department of Haematology and Transfusion Medicine of Mantua, Italy that kept records on people who underwent ABO blood typing during the period from January 2010 to December 2013.
the second study https://academic.oup.com/ajcp/article/135/1/96/1766172 … regards the ABO blood types of all patients who died a hospital in the United States in 2004 (the hospital is likely in or around Chapel Hill, NC based on making a search for it’s two authors). the goal in the second study was: “To assess the observation that blood type B might be a marker for longevity”…
“Based on a survey of 269 centenarians (people older than 100 years) living in Tokyo, Japan, it was suggested that blood type B might be a marker for longevity.1 To assess the validity and generalizability of this observation, we determined the ABO blood type of patients dying in our tertiary care hospital located in the United States. If blood group B was a marker of longevity, it would be expected that the percentage of patients with blood group B would increase with age at the time of death and the percentages of the other groups would decline. Similarly, it would be expected that the survival of patients with blood group B would differ significantly from patients with the other ABO blood groups.”
— some of the problems i see are this: there are less type B’s in the USA than there are in Japan by factor of 2 (maybe 10% in the USA vs 20% for Japan)…those who live past 100 are really in a class by themselves and quite uncommon. having more people like one’s self around is probably healthier. the study from Italy doesn’t measure ABO type based on death, but rather who went to the hospital and got blood type tested. both populations are small when compared to the population of Tokyo, Japan as a whole at ~ 9.2 million in 2015. the 269 centenarians divided by 9,200,000 is roughly = .0029% … and that’s a very small percentage. meaning who the-hell-knows what the truth is about the oldest people and their blood type – except going out there and testing them and seeing what the truth is now & as things change/time moves forward. the oldest person i’ve ever known personally was my mom’s mother who was A+ and died last year at the age of over 99 yrs + 1 month. so as has been said about some Italians, some Russian…villages and so on…they’re likely somewhat genetically related i would think…plus sometimes the place where one lives is very helpful to being healthy as well. know yourself well. that’s a good start imo.
i think i bumped into something else importance today. anyone ever heard of:
“The VWF gene provides instructions for making a blood clotting protein called von Willebrand factor. This protein contains regions that attach (bind) to specific cells and proteins during the formation of a blood clot.”
“Von Willebrand factor helps platelets stick together and adhere to the walls of blood vessels at the site of a wound. These groups of platelets form temporary clots, plugging holes in blood vessel walls to help stop bleeding. Von Willebrand factor also carries another blood clotting protein, coagulation factor VIII, to the area of clot formation.”
https://ghr.nlm.nih.gov/gene/VWF
What’s blood type got to do with clot risk?
By American Heart Association News … Published: January 23, 2020
https://www.heart.org/en/news/2020/01/23/whats-blood-type-got-to-do-with-clot-risk
“” People with blood types A and B may have higher risks for developing dangerous blood clots compared to people who have type O blood. That’s according to new research that also showed a slightly higher risk for certain types of heart disease among the A and B groups.
Past research has shown a likely link between heart disease and the ABO gene that exists in people with A, B or AB blood types, but not in people with type O blood. A 2017 preliminary study showed people with the ABO gene are at higher risk of heart attack during periods of heavy air pollution.
The new study of more than 400,000 people published Thursday in the American Heart Association journal Arteriosclerosis, Thrombosis, and Vascular Biology. Researchers found that compared to people with type O blood, those with types A or B had a combined 8% higher risk of heart attack and 10% increased risk of heart failure. “”
Blood Clots More Likely In AB Blood Types
AB blood type is a significant risk factor for venous thromboembolism, or blood clots, a new study suggests.
By Jaimie Dalessio Clayton …Last Updated: February 4, 2013
https://www.everydayhealth.com/heart-health/blood-clots-more-likely-in-ab-blood-types-9116.aspx
“Links between blood type, clotting (thrombosis), and its opposite, bleeding, may have to do with a blood component called von Willebrand levels, which are associated with bleeding, Dr. Blumberg explains. People with type O blood have the lowest von Willebrand levels (which make them more likely to bleed); those with AB blood have the highest levels (making them likely to clot); and people with type A and type B blood fall in between.”
Association of ABO blood groups with von Willebrand factor, factor VIII and ADAMTS-13 in patients with lung cancer
Published online 2017 Jul 20. … doi: 10.3892/ol.2017.6619
Xia Liu,1 Xiaogang Chen,2 Jiezuan Yang,3 and Renyong Guo2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587991/
“An association between the ABO blood group and blood coagulation was recognized several years previously. Non-O blood type has been associated with a significantly increased risk of venous and arterial thromboembolic disease, including deep vein thrombosis, pulmonary embolism, ischemic heart disease and peripheral vascular disease (9). The plasma levels of two coagulation glycoproteins, VWF and FVIII, have been demonstrated as the basis of this association between the ABO blood group and blood coagulation (10). Individuals with type O blood have significantly decreased plasma levels of VWF and FVIII, compared with those with non-O blood types (A, B and AB) (11). In total, ~66% of the variations in VWF plasma levels are associated with mutations, and 30% of these are associated with the effect of the ABO blood group (10).”
— i bring this subject up because CVD19 seems to cause micro-clots in many organs. this along w/ it binding to ACE2 receptors throughout the body and it seeking to screwing w/ the body’s immune system are what it’s past and current mutations have been doing/done. having blood that does not clot as easily seems to be an advantage in my mind currently when dealing w/ CVD19. —
Ken
Yes…good observations. As a B neg who has experienced atrial fibrillation and ablation surgery, these items are both personal and of broader significance.
As a personal anecdote, you and others may find this significant. In the post-op phase, i was prescribed a drug derived from Warfarin (rat poison). I had regular blood coagulation checks. Coagulation is very sensitive to diet, especially leafy greens….but also mangos. There is also a known genetic component.
When I had shaken off the top layers of medications, (being a naturopath) I was prescribed Lsinipril, which is a vassodilator, synthesized from the bio-chemistry of a Brazilian snake.
So it is just amazing what influences blood and cardiocascular diseases…and all efforts to understand them are fully justified.
I was not able to persuade the doctors to consider the role of RH Neg and blood groups.
A macro-perspective on this is that *IF* one accepts a large amount of Dr. Adamo’s theories on blood groups see
https://www.dadamo.com/txt/index.pl?1010
then it may be that we blood group B types do not do as well outside of our preferred (or original) habitats.
That raises interesting Lamarckian questions about adaptability and genes.
Richard, i had never really looked at Dr. Adamo’s theories or books before. i do believe it’s extremely important to know one’s self as well as is possible and do & be the things that work best for one’s self. so: upon going to his site and looking into some information about blood type O, i found this section most applicable and closest to me (Rh neg vs positive differences exist generally…i don’t think he gets that deep) – https://dadamo.com/txt/index.pl?1004
“” Energize – The Essential Exercise Component
Type O’s benefit tremendously from brisk regular exercise that taxes the cardiovascular and muscular skeletal system. But the benefit derived surpasses the goal of physical fitness. Type O also derives the benefit of a well timed chemical release system. The act of physical exercise releases a swarm of neurotransmitter activity that acts as a tonic for the entire system. The Type O who exercises regularly also has a better emotional response. You are more emotionally balanced as a result of well regulated, efficient chemical transport system. More than any other blood type, O’s rely on physical exercise to maintain physical health and emotional balance. Dr. D’Adamo suggests that Type O’s engage in regular physical activity three to four times per week. For best results, engage in aerobic activity for thirty to forty five minutes at least four times per week. If you are easily bored, choose two or three different exercises and vary your routine. “”
— i’m not that regimented. i’m more flexible w/ my routines, but in general i’m more physical fitness oriented more often throughout my day/night. my eccentricities shows-up in the way i exercise also…very self-adapted, original & created things. —
– more on things related to Lamarck –
History of evolutionary thought https://en.wikipedia.org/wiki/History_of_evolutionary_thought
Evolution: The Modern Synthesis https://en.wikipedia.org/wiki/Evolution:_The_Modern_Synthesis
Modern synthesis (20th century) https://en.wikipedia.org/wiki/Modern_synthesis_(20th_century)
Lamarckism https://en.wikipedia.org/wiki/Lamarckism#Lamarck's_evolutionary_framework
Transmutation of species https://en.wikipedia.org/wiki/Transmutation_of_species
On the Origin of Species https://en.wikipedia.org/wiki/On_the_Origin_of_Species
The Variation of Animals and Plants Under Domestication https://en.wikipedia.org/wiki/The_Variation_of_Animals_and_Plants_Under_Domestication
Mendelian inheritance https://en.wikipedia.org/wiki/Mendelian_inheritance
Weismann barrier https://en.wikipedia.org/wiki/Weismann_barrier
Genetic assimilation https://en.wikipedia.org/wiki/Genetic_assimilation
Somatic hypermutation https://en.wikipedia.org/wiki/Somatic_hypermutation
Epigenetics https://en.wikipedia.org/wiki/Epigenetics
Dual inheritance theory https://en.wikipedia.org/wiki/Dual_inheritance_theory
Baldwin effect https://en.wikipedia.org/wiki/Baldwin_effect
Genetic assimilation https://en.wikipedia.org/wiki/Genetic_assimilation
Hologenome theory of evolution https://en.wikipedia.org/wiki/Hologenome_theory_of_evolution
Ken:
Many thanks. yes…I like Adamo’s way of thinking but find him “off the mark” about 20% of the time. However his work does point in a good direction and one can filter out the 20%. I think that he is 100% “on the mark” with the idea that different blood types behave differently in many ways (food preferences, lifestyle, immune system) and that we each need to figure out what is best for us individually.
Otherwise stated, “eccentricty” is normal.
This has huge ramifications beyond the individual level…..calling into question the assumptions behind “herd immunity” (all humans are just a herd ) for example.
I like your list of citations. Some are already familiar and I will check into the others.
I see the broader philosophies as a critical part of understanding Rh Neg….specifically how and where it cam to be and how, when and where the mutations have evolved.
Closer to my current home (Bay Area California), I remember the intensity of the opposition to Linus Pauling’s ideas and efforts to “shut down” the idea of “punctuated evolution” and any evidence that supported it.
Richard, is this what you meant? – Gradualism and Punctuated Equilibrium – (in evolution)
https://necsi.edu/gradualism-and-punctuated-equilibrium
i think eccentricity is rather normal for some of the best, brightest & most original/creative/insightful Scientists/thinkers/artists & the like. yes, higher intellect – more creativity/insights/better understandings – more differentiated – often times, more different at/from the start, and if able to continue to be true to one’s own original self/being/interests…becoming more individualized, tends to imply or rather require becoming more eccentric – adjusting/adapting one’s self and one’s world around one to better suit/fit/satisfy … Rh(D) negs difs from the start of life, require differentiation from the vast majority of others often to live more satisfyingly. maybe eccentricity and greatness tend to exist simultaneously.
A lot of it has to do with an ability to observe. Whatever makes us different is hugely impacted by what most are unaware of. Inventions for example are often natural undiscovered phenomena rather than art. The ability to recognize stands out to me. Sometimes what seems obvious to us, most are oblivious to.
Ken:
Yes…that is what I was meant with regard to punctuated equilibrium.
It has a lot of ramifications for understanding the distribution and “evolution” of Rh Neg.
What would also be interesting to see is data on life expectancy by Rh factor based on country/location/region.
i’m still thinking about my comment on eccentricity & greatness…i think it’s better expressed like this:
eccentricity is to the potential to do great things, as arsenic is to finding a large high grade gold deposit.
eccentricity in no way guarantees one may be able to do great things; but it may indicate the potential for such if one is doing enough other positive things and finding a way to survive reasonably well in this world. from my experience: being eccentric is not easily achieved – in any way – unless one is able to spend much time alone for long periods (months/years) of time. for me: most interactions in my past were abrasive/wearing/annoying/not usually a satisfying enough experience. thus, i don’t interact much now and my life is actually/unfortunately better for it. i don’t seek greatness either. i seek to live a satisfying life (and being highly eccentric towards myself has worked better for me)…i’m interested in solving some problems i want to solve. i study what interests me as much and as often as possible and so on.
feigning eccentricity is to my mind like “fools gold”/iron pyrite. it may look like the real-thing initially, but upon closer examination one should see that it is fake and not real/not the same thing. live & learn and suit-yourself if you want & are able. none are the same…so what’s the dif’ really mean? anything? sometimes it does. w/ dif’s come magnitudes of variance. what does one use to measure? where does one start?
also, i do lots of observing – but, it’s my thinking upon something that allows me to gain insight/develop a better understands of the things i’m considering. sometimes i do have an “a-hah!”/light-bulb moment when i wasn’t really cogitating on something of my own choice. it’s usually by studying something well and thinking about in my own way & w/ my knowledge & experiences that i learn & learn something new. having new ideas is not uncommon for me. might as well use what one’s got, for such things don’t last – being mortal and all else.
yes Mike, it would be nice to know how all the Rh(D) neg blood types are doing based on country, city, region and so on health & age-wise. if everyone knew their blood type and enough commented on these subjects we’d certainly know & learn a lot more i think.
Mike:
Yes…such data would be great to have. Getting it is much more difficult. The primary clinical and data collection focus seems to be on Rh Neg mothers and blood transfusions…with little on life expectancy.
Ken:
The earth moves around the sun in an elliptical or eccentric orbit…and as such is the more correct pattern than circularity. I remind people of that when I hear criticism of human eccentricity. Nearly always they think that the earth orbits the sun in something close to a perfect circle!
Many thanks for the excellent Wikipedia references. One inescapable truth is that we are going through a true paradigm shift in genetics…and that it is productive to look at old data and conclusions with fresh eyes and the benefits of new (genomic) techniques.
“” Heparan sulfate (HS) is present on the surface of endothelial and surrounding tissues in large quantities. It plays important roles in regulating numerous functions of the blood vessel wall, including blood coagulation, inflammation response and cell differentiation. “” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876722/
and the reason why i’m posting here about heparan sulfate (this site & the article i’m linking to does not allow me to copy anything from it…so, here’s the link & a new study on heparan sulfate & CVD19) https://www.thailandmedical.news/news/covid-19-research-university-of-california-study-shows-that-heparan-sulfate-assists-sars-cov-2-coronavirus-to-bind-to-ace2-and-enter-human-host-cells