This is just something that I wish to clarify:There are families where she is Rh negative and he is Rh positive yet all of their 7 children are Rh positive.In such case, it is likely that the man would be Rh+/+ (homozygote), meaning he can only produce Rh positive children.Our study has shown the following:
Our study compared the health status of RhD negative subjects (16% in general population of Czech and Slovak Republics) with RhD positive subjects, i.e., with the health status of mixed population of RhD positive homozygotes (36% of the general populations within the Czech and Slovak Republics) and heterozygotes (48% the general populations in the Czech and Slovak Republics).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619848/
More here: http://rhnegative.bloodtypecalculator.com/
That means 64% within the population is either Rh negative or carries the gene, meaning that they are able to have Rh negative offspring. This often comes into play when someone asks me
“I am Rh negative, my husband is Rh positive, what are the chances of our next child being Rh negative like me”.
The answer:It depends.If he is +/-, then around 50%.
If he is +/+, the chances are 0%.
When the percentage of Rh negatives in a country is around 8.58% or less, the majority of the country will become Rh positive homozygotes (+/+).
No European country appears to have Rh- frequencies that low:
http://www.rhesusnegative.net/themission/bloodtypefrequencies/
For Africa and Asia, see also: