Diagram of the RHD and RHCE genes. The ten RHD exons are shown as white boxes, and the RHCE as grey. A). RHD and RHCE genes responsible for the common D, C, c, E and e antigen polymorphisms. B). Altered RHD and C). Altered RHCE genes indicating the changes often found in African-Americans that complicate transfusion, especially for sickle cell patients.
