Where or how did Rh- blood originate?

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Here’s the part of a Quora answer that actually made some sense:

How: Mutation of the RHD gene, resulting either in lack of expression of the protein or alteration in its structure making it less antigenic.


Where: Since there are a variety of such mutations in the human gene pool, it must have happened multiple times in multiple places. 

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3 Comments

  1. Richard Youatt July 6, 2021 Reply
  2. Lesley July 8, 2021 Reply
    • Mike DammannAuthor July 9, 2021 Reply

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